Elucidating identity and environmental fate of newly emerging chemicals (e.g. persistent (mobile) organics, polar surfactants, drugs of abuse, nanoparticles), and characterising structures of biotic and abiotic molecules, such as drug transformation products and plant biomarkers.
I coordinated the EU-FP6-NEST and industry funded projects PERFORCE-1 and 2, research projects aimed at the assessment of environmental exposure in Europe to perfluoroalkylated substances. I acted as coordinator of the EU-FP7-Agriculture/Food/Fisheries project PERFOOD that elucidated sources and extent of human exposure to perfluorinated compounds in food and beverages.
Since 2006 I also hold a position as Principal Scientist at KWR Watercycle Research Institute in Nieuwegein, where the focus of my research is on water quality and health issues related to newly emerging water contaminants, e.g., industrial chemicals, pharmaceuticals, and drugs of abuse. At KWR I coordinated the EU-DGHome project WATCH-Wastewater Analysis of Traces of illicit drug-related Chemicals for law enforcement and public Health through Wastewater-based epidemiology (WBE). I also coordinated a project for the World Anti-doping Agency (WADA) looking into development of methods for tracing doping in wastewater.
KWR and IBED jointly participate in the EU-COST action-sponsored network SCORE that coordinates WBE research to identify and assess the use and distribution of illicit drugs and counterfeit medicines in city populations. Non-target screening is another joint research area where we try to identify unkown chemicals in the water cycle.
I have been member-elect and treasurer of the Society of Environmental Toxicology and Chemistry-SETAC Europe.
I am a former member of the Dutch Soil Protection Committee (TCB) and the Scientific Committe on Health and Environmental Risks (SCHER) of the EC and a current member of the Scientific Committe on Health, Environmental and Emerging Risks (SCHEER). I am Editor-in-chief of the journal/book series Reviews of Environmental Contamination and Toxicology.
Hammer J, Haftka JJH, Scherpenisse P, Hermens JLM, de Voogt P (2017) Fragment-based approach to calculate hydrophobicity of anionic and nonionic surfactants derived from chromatographic retention on a C18 stationary phase. Environ. Toxicol. Chem. 36, 329-336. doi: 10.1002/etc.3564
Hoppe M, Fornari R, de Voogt P, Franz R (2017). Migration of oligomers from PET: determination of diffusion coefficients and comparison of experimental versus modelled migration. Food Addit. Contam. A 34, (in press) Doi: 0.1080/ 19440049.2017.1322222
Causanilles A, Ruepert C, Ibáñez M, Emke E, Hernández F, de Voogt P (2017) Occurrence and fate of illicit drugs and pharmaceuticals in wastewater from two wastewater treatment plants in Costa Rica. Sci. Total Environ. 599-600, 98-107 doi: 10.1016/j.scitotenv.2017.04.202
Rousis N, Gracia-Lor E, Zuccato E, Bade R, Baz-Lomba JA, Castrignanò E, Causanilles A, Covaci A, de Voogt P, Hernández F, Kasprzyk-Hordern B, Kinyua J, McCall AK, Plósz, BG, Ramin P, Ryu Y, Thomas KV, van Nuijs A, Yang Z, Castiglioni S (2017) Wastewater-based epidemiology to assess pan-European pesticide exposure. Water Res. 121, 270-279. doi: 10.1016/j.watres.2017.05.044
Ramin P, Brock AL, Causanilles A, Valverde-Pérez B, Emke E, de Voogt P, Polesel F, Plosz B (2017) Transformation and sorption of illicit drug biomarkers in sewer biofilms. Environ. Sci. Technol. (accepted) 10.1021/acs.est.6b06277
Causanilles A, Kinyua J, Ruttkies C, van Nuijs ALN, Emke E, Covaci A, de Voogt P (2017) Qualitative screening for new psychoactive substances in wastewater collected during a city festival using liquid chromatography coupled to high-resolution mass spectrometry. Chemosphere 184, 1186-1193. doi: 10.1016/ j.chemosphere. 2017.06.101
Refaey Y, Jansen B, de Voogt P, Parsons JR, El-Shater A, El-Haddad A, Kalbitz K (2017). The influence of organo-metal interactions on regeneration of exhausted sorbent materials loaded with heavy metals. Pedosphere 27, 579-587. doi:10.1016/S1002-0160(17)60353-9
Gracia-Lor E, Rousis N, Zuccato E, Bade R, Baz-Lomba JA, Castrignanò E, Causanilles A, Hernández F, Kasprzyk-Hordern B, Kinyua J, McCall AK, van Nuijs ALN, Plósz, BG, Ramin P, Ryu Y, Santos MM, Thomas KV, Yang Z, de Voogt P, Castiglioni S (2017) Estimation of caffeine intake from analysis of caffeine metabolites in wastewater. Sci. Total Environ. (accepted)
Bäuerlein PS , Emke E, Tromp P, Hofman JAMH , Carboni A, Schooneman F, de Voogt P, van Wezel AP (2017) Is there evidence for man-made nanoparticles in the Dutch environment? Sci. Total Environ. 576, 273-283
Markus AA, Parsons JR, Roex EW, de Voogt P, Laane RWPM (2017) Modelling the release, transport and fate of engineered nanoparticles in the aquatic environment – a review. Rev. Environ. Contam. Toxicol. (accepted) doi 10.1007/398_2016_17
Refaey Y, Jansen B, Parsons JR; de Voogt P, Bagnis S, Markus AA; El-Shater AH, El-Haddad AA; Kalbitz K. (2017)Effects of clay minerals, hydroxides, and timing of dissolved organic matter addition on the competitive sorption of Copper, Nickel and Zinc: A column experiment J. Environ. Manage. 187, 273-285. Doi:10.1016/j.jenvman.2016.11.056
Bade R, Bijlsma L, Sancho JV, Baz-Lomba JA, Castiglioni S, Castrignanò E, Causanilles A, Gracia-Lor E, Kasprzyk-Hordern B, Kinyua J, McCall A-K, van Nuijs ALN, Ort C, Plósz BG, Ramin P, Rousis NI, Ryu Y, Thomas KV, de Voogt P, Zuccato E, Hernandez F (2017) Liquid chromatography-tandem mass spectrometry determination of synthetic cathinones and phenethylamines in influent wastewater of eight European cities. Chemosphere 168, 1032-1041 doi: 10.1016/j.chemosphere.2016. 10.107
Dimzon IK, Westerveld J, Gremmel C, Frömel T, Knepper TP, de Voogt P (2017) Sampling and simultaneous determination of volatile per- and polyfluoroalkyl substances in wastewater treatment plant air and water. Anal. Bioanal. Chem. 409(5), 1395-1404. Doi: 10.1007/s00216-016-0072-1
Carboni A, Helmus R, Parsons JR, Kalbitz K, de Voogt P (2017). Incubation of solid state C60 fullerene under UV irradiation mimicking environmentally relevant conditions. Chemosphere 175, 1-7. Doi:10.1016/ j.chemosphere.2017.01.149
Sammut G, Sinagra E, Helmus R, de Voogt P (2017) Perfluoroalkyl substances in the Maltese Environment - (I) Surface water and Rain water. Sci. Total Environ. 589, 182-190.Doi: 10.1016/j.scitotenv.2017.02.128
Boix C, Ibáñez M,. Sancho JV, Parsons JR, de Voogt P, Hernández F (2016) Biotransformation of pharmaceuticals in surface water and during waste water treatment: identification and occurrence of transformation products. J. Haz. Mater. 302, 175-187. doi:10.1016/j.jhazmat.2015.09.053
Dimzon IK, Trier X, Frömel T, Helmus R, Knepper TP, de Voogt P (2016) High Resolution Mass Spectrometry of Polyfluorinated Polyether – based Formulation, J. Am. Soc. Mass Spectrom.27, 309-318. DOI: 10.1007/s13361-015-1269-9
Hoppe M; de Voogt P, Franz R (2016) Identification and quantification of oligomers as potential migrants in plastics food contact materials with a focus in polycondensates - A review. Trends Food Sci. Technol. 50, 118-130, doi: 10.1016/ j.tifs. 2016.01.018
Markus AA, Parsons JR, Roex EW, de Voogt P, Laane RWPM (2016) Modelling the transport of engineered metallic nanoparticles in the river Rhine. Water Res. 91, 214-224
Bade R, Causanilles A, Emke E, Bijlsma L, Sancho JV, Hernández F, de Voogt P (2016) Facilitating high resolution mass spectrometry data processing for screening of environmental water samples: An evaluation of two deconvolution tools. Sci. Total Environ. 569–570, 434–441
Carboni A, Helmus R, Parsons JR, Kalbitz K, de Voogt P (2016) A method for the determination of fullerenes in soil and sediment matrices using ultra-high performance liquid chromatography coupled with heated electrospray quadrupole time of flight mass spectrometry. J. Chromatogr. A 1433, 123-130
Causanilles A, Emke E, de Voogt P (2016) Determination of phosphodiesterase type V inhibitors in wastewater by direct injection followed by liquid chromatography coupled to tandem mass spectrometry. Sci. total Environ. 565, 140-147
Ryu Y, Barceló D, Barron LP, Bijlsma L, Castiglioni S, de Voogt P, Emke E, Hernández F, Lai, FY, Lopes A, López de Alda M, Mastroianni N, Munro K, O’Brien J, Ort C, Plósz BG, Reid MJ, Yargeau V, Thomas KV (2016) Comparative measurement and quantitative risk assessment of alcohol consumption through wastewater-based epidemiology: An international study in 20 cities. Sci. Total Environ. 565, 977–983
Hammer J, Haftka JJH, Scherpenisse P, Hermens JLM, de Voogt P (2016) Fragment-based approach to calculate hydrophobicity of anionic and nonionic surfactants derived from chromatographic retention on a C18 stationary phase. Environ. Toxicol. Chem. DOI: 10.1002/etc.3564
Vughs D, Baken KA, Kolkman A, Martijn AJ, de Voogt P (2016) Application of effect directed analysis to identify mutagenic nitrogenous disinfection byproducts of MP UV drinking water treatment. Environ. Sci. Pollut. Res. (in press) doi:10.1007/ s11356-016-7252-6
Carboni A, Helmus R, Emke E, van den Brink N, Parsons JR, Karsten Kalbitz K, de Voogt P (2016) Analysis of fullerenes in soils samples collected in The Netherlands. Environ. Pollut. 219, 47-55. doi: 10.1016/j.envpol.2016.09.034
Reemtsma T, Berger U, Arp HPH, Gallard H, Knepper TP, Neumann M, Quintana JB, de Voogt P (2016) Mind the Gap: Persistent and Mobile Organic Compounds—Water Contaminants That Slip Through. Environ. Sci. Technol. 50, 10308-10315. Doi: 10.1021/acs.est.6b03338
Baz Lomba JA, Salvatore S, Bade R, Castiglioni S, Castrignanò E, Causanilles A, Gracia-Lor E, Hernandez F, Kasprzyk-Hordern B, Kinyua J, McCall A-K, van Nuijs A, Ort C, Plósz BG, Ramin P, Reid M, Ryu, Y, de Voogt P, Bramness J, Thomas K (2016) Comparison of pharmaceutical, illicit drug, alcohol, nicotine and caffeine levels in wastewater with sale, seizure and consumption data for 8 European cities. BMC Publ. Health 16:1035. doi: 10.1186/s-12889-016-3686-5
Kinyua J, Negreira N, Miserez B, Causanilles A, Emke E, de Voogt P, Ramsey J, Covaci A, van Nuijs ALN (2016) Qualitative screening of pooled urine samples in Belgium and United Kingdom to map the use of new psychoactive substances Sci. Total Environ. 573, 1527-1535. doi: 10.1016/j.scitotenv.2016.08.124
Hernández F, Castiglioni S, Covaci A, de Voogt P, Emke E, Kasprzyk-Hordern B, Ort C, Reid M, Sancho JV, Thomas KV, van Nuijs ALN, Zuccato E, Bijlsma L (2016) Mass spectrometric strategies for the investigation of biomarkers of illicit drug use in wastewater. Mass Spectrom. Rev. (accepted) doi: 10.1002/mas.21525
Ramin P, Libonati Brock A, Polesel F, Causanilles A, Emke E, de Voogt P, Plósz BG (2016) Transformation and sorption of illicit drug biomarkers in sewer systems: understanding the role of suspended solids in raw wastewater. Environ. Sci. Technol. 50, 13397−13408. Doi 10.1021/acs.est.6b03049
Ryu Y, Gracia-Lor E, Bijlsma L, Baz-Lomba JA, Bramness JG, Castiglioni S, Castrignanò E, Causanilles A, Covaci A, de Voogt P, Hernández F, Kasprzyk-Hordern B, Kinyua J, McCall A-K, Ort C, Plósz BG, Ramin P, Roussos NI, Reid MJ, Thomas KV (2016) Increased levels of the oxidative stress biomarker 8-iso-prostaglandin F2α in wastewater associated with tobacco use. Sci. Reports 6:39055
Hofman-Caris CHM, Bäuerlein PS, Siegers WG, Ziaie J, Tolkamp HH, de Voogt P (2015) Affinity adsorption for the removal of organic micropollutants in drinking water sources; proof of principle. Water Sci. Technol.:Water Supply 15.6, 1207-1219
Krätke R, Bartonova A, Beausoleil C, Carroquino MJ, de Voogt P, Duarte-Davidson R, Fernandes T, Gzyl J, Janssen C, Linders J, Schoeters G (2015) Does the EU migration level of chromium VI in toys need to be lowered? Regulat. Toxicol. Pharmacol. 73, 687-688
Ten Tusscher GW, Leijs MM, Koppe JG, Olie K, de Voogt P, Van Aalderen WCM (2015) Decrease in lung function in relation to increasing BDE exposure in teenagers. Eur. Respir. J. 46 (Suppl 59):PA4097
Astefanei A, Kok W, Bäuerlein PS, Nunez O, Galceran M,de Voogt P, Schoenmakers P (2015) Characterization of aggregates of surface modified fullerenes by asymmetrical flow field-flow fractionation with multi angle light scattering detection. J. Chromatogr. A 1408, 197-206
Cousins IT, Balan SA, Scheringer M, Weber R, Wang Z, Blum A, Diamond M, Fletcher T, Goldenman G, Higgins C, Lindeman AE, Peaslee G, Trier X, de Voogt P (2015) Comment on "Fluorotechnology Is Critical to Modern Life: The FluoroCouncil Counterpoint to the Madrid Statement". Environ. Health Perspect.123, A170
Emke E, Sanchis J, Farré M., Bäuerlein PS, de Voogt P (2014) Determination of several fullerenes in sewage water by LC hr-MS using atmospheric pressure photo ionisation. Environ. Sci. Nano 2, 167-176.
Blum A, Balan SA, Scheringer M, Trier X, Goldenman G, Cousins I, Diamond M, Fletcher T, Higgins C, Lindeman AE, Peaslee G, de Voogt P, Wang Z, Weber R (2015) The Madrid Statement on Poly- and Perfluoroalkyl Substances. Environ. Health Perspect.123, A107-A111.
Herrero P, Bäuerlein PS, Emke E, Marcé RM, de Voogt P (2015) Size and concentration determination of (functionalized) fullerenes in surface and sewage water matrices using field flow fractionation coupled to an online accurate mass spectrometer: method development and validation. Anal. Chim. Acta 871, 77-84.
Booij P, Sjollema SB, van der Geest HG, Leonards PEG, Lamoree MH, de Voogt P, Admiraal W, Laane RWPM, Vethaak AD (2015) Toxic pressure of herbicides on microalgae in Dutch estuarine and coastal waters. J. Sea Res. 102, 48-56.
Haftka JJH, Bäuerlein PS, Emke E, Lammertse N, Belokhovstova D, Hilvering B, de Voogt P, ter Laak TL (2015) Colloidal stability of (functionalised) fullerenes in the presence of dissolved organic carbon and electrolytes. Environ. Sci. Nano 2, 280-287.
Korsman J, Schipper AM, de Vos MG, van den Heuvel-Greve MJ, Vethaak AD, de Voogt P, Hendriks AJ. (2015) Modeling accumulation of nonylphenol and its ethoxylates in estuarine-marine food chains. Chemosphere 138, 33-39.
Markus AA, Parsons JR, Roex EWM,de Voogt P, Laane RWPM (2015) Modelling aggregation and sedimentation of nanoparticles in the aquatic environment Sci. Total Environ. 506–507, 323–329
Barmentlo SH, Stel JM, van Doorn M, Eschauzier C, de Voogt P, Kraak MHS (2015) Acute and chronic toxicity of short chained perfluoroalkyl substances to Daphnia magna. Environ. Pollut. 198, 47-53
Jansen M, Coors A, Vanoverbeke J, Schepens M, de Voogt P, De Schampelaere KAC, De Meester L (2013) Experimental evolution reveals high insecticide tolerance in Daphnia inhabiting farmland ponds. Evol. Appl. 8, 442-453
D’Hollander W, Herzke D, Huber S, Hajslova J, Pulkrabova J, Brambilla G, De Filippis SP, Bervoets L,de Voogt P (2014) Occurrence of perfluorinated alkylated substances in cereals, salt, sweets and fruit items collected in four European countries. Chemosphere 129, 179-185
Terzic, O, Gregg H, de Voogt P (2015) Identification of chemicals relevant to the Chemical Weapons Convention: novel sample preparation methods and strategies of the mobile laboratory of the Organisation for the Prohibition of Chemical Weapons. Trends Anal Chem 65, 151-166
Venhuis BJ, de Voogt P, Emke E, Causanilles A, Keizers PHJ (2014) Success of rogue online pharmacies: sewage study of sildenafil in The Netherlands. Brit. Med. J. 349:g4317
Herrero P, Bäuerlein PS, Emke E, Pocurull E, de Voogt P (2014) Asymmetrical flow field-flow fractionation hyphenated to Orbitrap high resolution mass spectrometry for the determination of (functionalised) aqueous fullerene aggregates. J. Chromatogr. A 1356, 277-282.
Jurgens SS, Helmus R, Waaijers SL, Uittenbogaard D, Dunnebier D, Vleugel M,. Kraak MHS, de Voogt P, Parsons JR (2014) Mineralisation and primary biodegradation of aromatic organophosphorus flame retardants in activated sludge. Chemosphere 111, 238-24
Booij,P, Vethaak AD, Leonards PEG, Sjollema S, Kool J, de Voogt P, Lamoree M (2014) Inhibition of photosynthesis inhibitors of pelagic marine algae using 96 well plate micro-fractionation for enhanced throughput in Effect-Directed Analysis. Environ Sci Technol 48, 8003-8011
Leijs MM, van der Linden LM, Koppe JG, de Voogt P, Olie K, van Aalderen WMC, ten Tusscher GW (2014) The influence of perinatal and current dioxin and PCB exposure on puberty: a review. Biomonitoring 1, 16-24
Carboni A, Emke E, Parsons JR, Kalbitz K, de Voogt P (2014) An analytical method for determination of fullerenes and functionalized fullerenes in soils with HPLC-UV. Anal Chim Acta 807, 159-165
Prichard J, Hall W, de Voogt P, Zuccato E (2014) Sewage epidemiology and illicit drug research: the development of ethical research guidelines. Sci. Total Environ. 472, 550-555
Emke E, Evans S, Kasprzyk-Hordern B, de Voogt P (2014) Enantiomer profiling of high loads of amphetamine and MDMA in communal sewage: a Dutch perspective Sci. Total Environ. (in press) http://dx.doi.org/10.1016/j.scitotenv.2013.11.043
D’Hollander W, De Bruyn L, Hagenaars A, de Voogt P, Bervoets L (2014) Characterisation of perfluorooctane sulfonate (PFOS) in a terrestrial ecosystem near a fluorochemical plant in Flanders, Belgium. Environ. Sci. Pollut. Res. ( accepted) DOI 10.1007/s11356-013-2449-4
Felizeter S, McLachlan M, de Voogt P (2014) Root uptake and translocation of perfluorinated alkyl acids by three hydroponically grown crops. J. Agric. Food Chem. 62, 3334-3342
Booij P, Sjollema SB , Leonards PEG, de Voogt P, Stroomberg GJ, Vethaak AD, Lamoree MH (2013) Extraction Tools for Identification of Chemical Contaminants in Estuarine and Coastal Waters to Determine Toxic Pressure on Primary Producers. Chemosphere 93, 107-114
Waaijers SL, Bleyenberg TE, Dits A, Schoorl M, Schütt J, Kools S, de Voogt P, Admiraal W, Parsons JR, Kraak MHS (2013) Daphnid life cycle responses to new generation flame retardants. Environ. Sci. Technol. 47, 13798-13803.
Klenow S, Heinemeyer G, Brambilla G, Dellatte E, Herzke D, de Voogt P (2013) Dietary exposure to selected Perfluoroalkyl acids (PFAAs) in four European regions Food Addit. Contam. A 30, 2141-2151
Kolkman A, Schriks M, Brand W , Bäuerlein PS, van der Kooi MME, van Doorn RH , Emke E, Reus A, van der Linden S, de Voogt P, Minne B. Heringa MB (2013) Sample preparation for combined chemical analysis and bioassay application in water quality assessment. Environ Toxicol Pharmacol. 36, 1291-1303
Kolkman A, Emke E, Bäuerlein P, Carboni A, Truc Tran D, Ter Laak T, van Wezel A, de Voogt P (2013) Analysis of (functionalized) fullerenes in water samples by liquid chromatography coupled to high resolution mass spectrometry. Anal. Chem. 85, 5867-5874
Bijlsma L, Emke E, Hernández F, de Voogt P (2013) Performance of the linear ion trap Orbitrap mass analyzer for qualitative and quantitative analysis of drugs of abuse and relevant metabolites in sewage water. Anal. Chim. Acta 768, 102– 110
Eschauzier C, Hoppe M, Schlummer M, de Voogt P (2013). Presence and sources of anthropogenic perfluorinated alkyl acids in tap-water based beverages. Chemosphere, 90, 36-41.
Castiglioni S, Bijlsma L, Covaci A, Emke E, Hernández F, Reid M, Ort C, Thomas KV, van Nuijs ALN, de Voogt P, Zuccato E (2013) Evaluation of Uncertainties Associated with the Determination of Community Drug Use through the Measurement of Sewage Drug Biomarkers. Environ. Sci. Technol. 47, 1452-1460
Waaijers SL, Kong D, Hendriks HS, de Wit CA, Cousins IT, Westerink RHS, Kraak MHS, Admiraal W, Leonards PEG, de Voogt P, Parsons JR (2013). Persistence, bioaccumulation and toxicity of halogen-free flame retardants. Rev Environ Contam Toxicol, 222, 1-71.
van der Aa NGFM, Bijlsma L, Emke E, Dijkman E, ; van Nuijs ALN, van de Ven BM, Hernández F; Versteegh A; de Voogt P (2013) Risk assessment for drugs of abuse in the Dutch watercycle. Water Res. 47, 1848-1857
Eschauzier C, Raat KJ, Stuyfzand PJ, de Voogt P (2013) Perfluorinated alkylated acids in groundwater and drinking water: identification, origin and mobility. Sci Total Environ 458-460, 477-485
Herzke D, Huber S, Bervoets L, D’Hollander W, Hasjlova J, Pulkrabova J, Brambilla G, De Filippis SP, Klenow S, Heinemeyer G, de Voogt P (2013) PFAS in vegetables collected in four European countries; raw and processed products. Environ Sci Pollut Res 20, 7930-7939.
Hlouskova V, Hradkova P, Poustka J, Brambilla G, De Filippis SP, D´Hollander W, Bervoets L, Herzke D, Huber S, de Voogt P, Pulkrabova J (2013) Occurrence of PFASs in various food items of animal origin collected in four European countries. Food Addit. Contam.A 30, 1918-1932
Brulik J, Simek Z, de Voogt P (2013) A new liquid chromatography – tandem mass spectrometry method using atmospheric pressure photo ionization for simultaneous determination of azaarenes and azaarones in Dutch river sediments. J. Chromatogr. A 1294, 33-40
Schriks M, van der Linden S, Stoks P, van der Burg B, Puijker L, de Voogt P, Heringa MB (2013) Occurrence of glucocorticogenic activity in various surface waters in The Netherlands. Chemosphere 93, 450-454
Terzic O, Bartenbach S, de Voogt P (2013) Determination of Lewisites and their hydrolysis products in aqueous and multiphase samples by in-sorbent tube butyl thiolation followed by thermal desorption-gas chromatography-full scan mass spectrometry. J. Chromatog. A 1304, 34-41
Dellatte E, Brambilla G, De Filippis SP, di Domenico A, Pulkrabova J, Eschauzier C, Klenow S, Heinemeyer G, de Voogt P (2013) Occurrence of selected perfluorinated alkyl acids in lunch meals served at school canteens in Italy and their relevance for children’s intake. Food Addit. Contam. A 30, 1590-1597